How does click chemistry work?
Click chemistry :
Click chemistry aims to find simple, fast and flexible methods for clipping molecules together through robust links. Polish researchers have succeeded in applying this same method on a larger scale, to fix gold nanoparticles to a solid carbon substrate.
Theclick is a relatively new method of . It draws on the “buttons ” chemical to bind small molecular modules and build customized structures quickly and efficiently.
This method was previously used mainly for the synthesis of complex.
Researchers from theof the Polish Academy of Sciences (SAP IPC) Warsaw managed to apply the principle of to they so fixed on a of .
The idea of click chemistry was born at the end of the last century. It is inspired by nature and especially the structure of.
They consist of chains ofall formed from the same type of bonds between an of and an atom of . The establishment of these so-called peptide bonds is facilitated by the action of .
The click chemistry mimics the processes for the synthesis of organic compounds, like children build a structure using small block. The benefits are many.
The reactions generally take place at room temperature and in aunique that often comes down to water. The reaction yield is particularly high since it is around 80 to 90%.
The IPC PAS team wanted to apply these principles to bulk bricks larger thanand sought to fix gold on a substrate .
Conventionally, the nanoparticles are simply deposited on the substrate and then attached thereto through weak physical links,for example.
Thanks to click chemistry, Polish researchers have managed to fix the nanoparticles to their substrate by durable.
Stable carbon-nitrogen bonds
To achieve this result, the IPC PAS team used well-known chemical snaps. Groups formed of three nitrogen atoms, azides, are indeed likely, in the presence of a, to bind with groups of carbon atoms, acyls, located at the ends of various molecules to form particularly stable carbon-nitrogen bonds.
Here, the azides were added to the vitreous carbon substrate and the acyls to the gold nanoparticles.
Theis based in turn on an electrochemical process. The whole process could be optimized so that the nanoparticles suspended around the remain stable and the concentration of in the electrolyte remains the best.
The use of electrochemistry rather than a more conventional chemical catalyst has also reduced the reaction time.
The work of the IPC PAS team could already make it possible to develop conservative detectors such as sulphites, effective and simple.
Polish researchers claim that their method is equally applicable to other substrates. What to consider the development of different types of chemical.